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siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells
BACKGROUND: Doxorubicin is an effective breast cancer drug but is hampered by a severe, dose-dependent toxicity. Concomitant administration of doxorubicin and another cancer drug may be able to sensitize tumor cells to the cytotoxicity of doxorubicin and lowers the therapeutic dosage. In this study,...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691745/ https://www.ncbi.nlm.nih.gov/pubmed/19416503 http://dx.doi.org/10.1186/1471-2407-9-133 |