Cargando…

Direct experimental evidence for quadruplex–quadruplex interaction within the human ILPR

Here we report the analysis of dual G-quadruplexes formed in the four repeats of the consensus sequence from the insulin-linked polymorphic region (ACAGGGGTGTGGGG; ILPR(n)(=4)). Mobilities of ILPR(n)(=4) in nondenaturing gel and circular dichroism (CD) studies confirmed the formation of two intramol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schonhoft, Joseph D., Bajracharya, Rabindra, Dhakal, Soma, Yu, Zhongbo, Mao, Hanbin, Basu, Soumitra
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691825/ https://www.ncbi.nlm.nih.gov/pubmed/19324891 http://dx.doi.org/10.1093/nar/gkp181

Ejemplares similares

Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions
por: Dhakal, Soma, et al.
Publicado: (2013)

Intramolecular Folding in Human ILPR Fragment with Three C-Rich Repeats
por: Dhakal, Soma, et al.
Publicado: (2012)

Towards Computational Modeling of Ligand Binding to the ILPR G-Quadruplex
por: Zhang, Xiaotong, et al.
Publicado: (2023)

Nascent RNA transcripts facilitate the formation of G-quadruplexes
por: Shrestha, Prakash, et al.
Publicado: (2014)

Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes
por: Šket, Primož, et al.
Publicado: (2012)

Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation
por: Cian, Anne De, et al.
Publicado: (2007)

Direct visualization of G-quadruplexes in DNA using atomic force microscopy
por: Neaves, Kelly J., et al.
Publicado: (2009)

Stability and kinetics of G-quadruplex structures
por: Lane, Andrew N., et al.
Publicado: (2008)

Bulges in left-handed G-quadruplexes
por: Das, Poulomi, et al.
Publicado: (2021)

Structural polymorphism of intramolecular quadruplex of human telomeric DNA: effect of cations, quadruplex-binding drugs and flanking sequences
por: Gaynutdinov, Timur I., et al.
Publicado: (2008)

NMR evaluation of ammonium ion movement within a unimolecular G-quadruplex in solution
por: Podbevšek, Peter, et al.
Publicado: (2007)

A direct view of the complex multi-pathway folding of telomeric G-quadruplexes
por: Aznauryan, Mikayel, et al.
Publicado: (2016)

Two cationic porphyrin isomers showing different multimeric G-quadruplex recognition specificity against monomeric G-quadruplexes
por: Huang, Xiao-Xi, et al.
Publicado: (2014)

Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes
por: Dickerhoff, Jonathan, et al.
Publicado: (2021)

Folding and misfolding pathways of G-quadruplex DNA
por: Marchand, Adrien, et al.
Publicado: (2016)

Duplex formation in a G-quadruplex bulge
por: Ngoc Nguyen, Thi Quynh, et al.
Publicado: (2020)

Water spines and networks in G-quadruplex structures
por: Li, Kevin, et al.
Publicado: (2020)

Kinetics and mechanism of G-quadruplex formation and conformational switch in a G-quadruplex of PS2.M induced by Pb(2+)
por: Liu, Wei, et al.
Publicado: (2012)

Solution structure of the major G-quadruplex formed in the human VEGF promoter in K(+): insights into loop interactions of the parallel G-quadruplexes
por: Agrawal, Prashansa, et al.
Publicado: (2013)

Quadruplexes in ‘Dicty’: crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome
por: Guédin, Aurore, et al.
Publicado: (2018)

Stability of intramolecular quadruplexes: sequence effects in the central loop
por: Guédin, Aurore, et al.
Publicado: (2009)

Guanine base stacking in G-quadruplex nucleic acids
por: Lech, Christopher Jacques, et al.
Publicado: (2013)

G-quadruplex structure of an anti-proliferative DNA sequence
por: Do, Ngoc Quang, et al.
Publicado: (2017)

Structure of two G-quadruplexes in equilibrium in the KRAS promoter
por: Marquevielle, Julien, et al.
Publicado: (2020)

A DNA G-quadruplex/i-motif hybrid
por: Chu, Betty, et al.
Publicado: (2019)

Sugar-modified G-quadruplexes: effects of LNA-, 2′F-RNA– and 2′F-ANA-guanosine chemistries on G-quadruplex structure and stability
por: Li, Zhe, et al.
Publicado: (2014)

A thermodynamic overview of naturally occurring intramolecular DNA quadruplexes
por: Kumar, Niti, et al.
Publicado: (2008)

Crystallization and characterization of the thallium form of the Oxytricha nova G-quadruplex
por: Gill, Michelle L., et al.
Publicado: (2006)

Intramolecular DNA quadruplexes with different arrangements of short and long loops
por: Rachwal, Phillip A., et al.
Publicado: (2007)

Engineering of interlocked DNA G-quadruplexes as a robust scaffold
por: Phan, Anh Tuân, et al.
Publicado: (2013)

G-quadruplex conformation and dynamics are determined by loop length and sequence
por: Tippana, Ramreddy, et al.
Publicado: (2014)

Flexibility and structural conservation in a c-KIT G-quadruplex
por: Wei, Dengguo, et al.
Publicado: (2015)

Organelle-mimicking liposome dissociates G-quadruplexes and facilitates transcription
por: Pramanik, Smritimoy, et al.
Publicado: (2014)

Coexistence of two quadruplex–duplex hybrids in the PIM1 gene
por: Tan, Derrick J Y, et al.
Publicado: (2020)

Guiding the folding of G-quadruplexes through loop residue interactions
por: Jana, Jagannath, et al.
Publicado: (2022)

c-MYC promoter G-quadruplex formed at the 5′-end of NHE III(1) element: insights into biological relevance and parallel-stranded G-quadruplex stability
por: Mathad, Raveendra I., et al.
Publicado: (2011)

Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism
por: Yang, Qianfan, et al.
Publicado: (2010)

Effect of loop length variation on quadruplex-Watson Crick duplex competition
por: Kumar, Niti, et al.
Publicado: (2008)

Natural isoflavones regulate the quadruplex–duplex competition in human telomeric DNA
por: Zhang, Jin-li, et al.
Publicado: (2009)

Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures
por: Esposito, Veronica, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_h70se2fotmsp8eb2cmn12p02cp