Cargando…

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions

Translation initiation in eukaryotes is mediated by assembly of the eIF4F complex over the m(7)GTP cap structure at the 5′-end of mRNAs. This requires an interaction between eIF4E and eIF4G, two eIF4F subunits. The Leishmania orthologs of eIF4E are structurally diverged from their higher eukaryote c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoffe, Yael, Léger, Mélissa, Zinoviev, Alexandra, Zuberek, Joanna, Darzynkiewicz, Edward, Wagner, Gerhard, Shapira, Michal
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691829/ https://www.ncbi.nlm.nih.gov/pubmed/19321500 http://dx.doi.org/10.1093/nar/gkp190

Ejemplares similares

Synergistic activation of eIF4A by eIF4B and eIF4G
por: Nielsen, Klaus H., et al.
Publicado: (2011)

eIF4E3 forms an active eIF4F complex during stresses (eIF4F(S)) targeting mTOR and re-programs the translatome
por: Weiss, Benjamin, et al.
Publicado: (2021)

Distinct Features of Cap Binding by eIF4E1b Proteins
por: Kubacka, Dorota, et al.
Publicado: (2015)

Characterization of an Atypical eIF4E Ortholog in Leishmania, LeishIF4E-6
por: Tupperwar, Nitin, et al.
Publicado: (2021)

eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei
por: Freire, Eden R., et al.
Publicado: (2014)

eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle
por: Harms, Ulf, et al.
Publicado: (2014)

RNA-tethering assay and eIF4G:eIF4A obligate dimer design uncovers multiple eIF4F functional complexes
por: Robert, Francis, et al.
Publicado: (2020)

Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA
por: Izidoro, Mario Servulo, et al.
Publicado: (2022)

Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E
por: Gosselin, Pauline, et al.
Publicado: (2013)

Expression of phosphorylated eIF4E-binding protein 1, but not of eIF4E itself, predicts survival in male breast cancer
por: Millican-Slater, Rebecca A, et al.
Publicado: (2016)

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F
por: Chu, Jennifer, et al.
Publicado: (2020)

Human Translation Initiation Factor eIF4G1 Possesses a Low-Affinity ATP Binding Site Facing the ATP-Binding Cleft of eIF4A in the eIF4G/eIF4A Complex
por: Akabayov, Sabine R., et al.
Publicado: (2014)

Loss-of-Function Analysis Reveals Distinct Requirements of the Translation Initiation Factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila Spermatogenesis
por: Ghosh, Sanjay, et al.
Publicado: (2015)

Selectivity for eIF4E
por: LeBrasseur, Nicole
Publicado: (2005)

The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells
por: González-Almela, Esther, et al.
Publicado: (2018)

The eIF4F and eIFiso4F Complexes of Plants: An Evolutionary Perspective
por: Patrick, Ryan M., et al.
Publicado: (2012)

Signalling to eIF4E in cancer
por: Siddiqui, Nadeem, et al.
Publicado: (2015)

Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer
por: Wagner, Susan, et al.
Publicado: (2016)

An intramolecular disulphide bond in human 4E-T affects its binding to eIF4E1a protein
por: Zuberek, Joanna, et al.
Publicado: (2023)

The domains of yeast eIF4G, eIF4E and the cap fine-tune eIF4A activities through an intricate network of stimulatory and inhibitory effects
por: Krause, Linda, et al.
Publicado: (2022)

Metformin blocks MYC protein synthesis in colorectal cancer via mTOR‐4EBP‐eIF4E and MNK1‐eIF4G‐eIF4E signaling
por: Shen, Peng, et al.
Publicado: (2018)

eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling
por: Attar-Schneider, Oshrat, et al.
Publicado: (2015)

Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E
por: Ma, Xuhui, et al.
Publicado: (2019)

eIF4E-eIF4G complex inhibition synergistically enhances the effect of sorafenib in hepatocellular carcinoma
por: Fang, Chao, et al.
Publicado: (2021)

The eIF4EBP-eIF4E axis regulates CD4(+) T cell differentiation through modulation of T cell activation and metabolism
por: Istomine, Roman, et al.
Publicado: (2023)

The translational factor eIF3f: the ambivalent eIF3 subunit
por: Marchione, Roberta, et al.
Publicado: (2013)

4E-BP restrains eIF4E phosphorylation
por: Müller, David, et al.
Publicado: (2013)

eIF4E Phosphorylation in Prostate Cancer()()
por: D'Abronzo, Leandro S., et al.
Publicado: (2018)

Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast
por: Grüner, Stefan, et al.
Publicado: (2018)

The eIF3 complex of Leishmania—subunit composition and mode of recruitment to different cap-binding complexes
por: Meleppattu, Shimi, et al.
Publicado: (2015)

SUMO-2 Promotes mRNA Translation by Enhancing Interaction between eIF4E and eIF4G
por: Chen, Li-zhao, et al.
Publicado: (2014)

Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo
por: Gulay, Suna, et al.
Publicado: (2020)

Enzymatic and Molecular Characterization of Anti-Leishmania Molecules That Differently Target Leishmania and Mammalian eIF4A Proteins, LieIF4A and eIF4A(Mus)
por: Abdelkrim, Yosser Zina, et al.
Publicado: (2022)

Translation Directed by Hepatitis A Virus IRES in the Absence of Active eIF4F Complex and eIF2
por: Redondo, Natalia, et al.
Publicado: (2012)

Combined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity
por: Coleman, L J, et al.
Publicado: (2009)

The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior
por: Wiebe, Shane, et al.
Publicado: (2020)

Synthesis of Rigidified eIF4E/eIF4G Inhibitor-1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction
por: Mahalingam, Poornachandran, et al.
Publicado: (2014)

Dendritic eIF4E-binding Protein 1 (eIF4E-BP1) mRNA Is Upregulated by Neuronal Activation
por: Moon, Il Soo, et al.
Publicado: (2012)

Translation, Pdcd4 and eIF4A
por: Biyanee, Abhiruchi, et al.
Publicado: (2015)

Correction: SUMO-2 Promotes mRNA Translation by Enhancing Interaction between eIF4E and eIF4G
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_nvmeq6balueq32gl5p9gv48t0f