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CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding

The proline-rich homeodomain protein (PRH/Hex) regulates transcription by binding to specific DNA sequences and regulates mRNA transport by binding to translation initiation factor eIF4E. Protein kinase CK2 plays multiple roles in the regulation of gene expression and cell proliferation. Here, we sh...

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Detalles Bibliográficos
Autores principales:	Soufi, Abdenour, Noy, Peter, Buckle, Malcolm, Sawasdichai, Anyaporn, Gaston, Kevin, Jayaraman, Padma-Sheela
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691835/ https://www.ncbi.nlm.nih.gov/pubmed/19324893 http://dx.doi.org/10.1093/nar/gkp197

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