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Identification of HCV protease inhibitor resistance mutations by selection pressure-based method

A major challenge to successful antiviral therapy is the emergence of drug-resistant viruses. Recent studies have developed several automated analyses of HIV sequence polymorphism based on calculations of selection pressure (K(a)/K(s)) to predict drug resistance mutations. Similar resistance analysi...

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Detalles Bibliográficos
Autores principales:	Qiu, Ping, Sanfiorenzo, Vincent, Curry, Stephanie, Guo, Zhuyan, Liu, Shaotang, Skelton, Angela, Xia, Ellen, Cullen, Constance, Ralston, Robert, Greene, Jonathan, Tong, Xiao
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691846/ https://www.ncbi.nlm.nih.gov/pubmed/19395595 http://dx.doi.org/10.1093/nar/gkp251

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