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Automated screening for mutants affecting dopaminergic neuron specification in C. elegans

We describe an automated method to isolate mutant C. elegans animals, which fail to appropriately execute a cellular differentiation program that we monitor with gfp-based reporter gene technology. A fluorescence activated sorting mechanism implemented in the COPAS Biosort machine is able to isolate...

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Detalles Bibliográficos
Autores principales:	Doitsidou, Maria, Flames, Nuria, Lee, Albert C., Boyanov, Alexander, Hobert, Oliver
Formato:	Texto
Lenguaje:	English
Publicado:	2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693092/ https://www.ncbi.nlm.nih.gov/pubmed/18758453 http://dx.doi.org/10.1038/nmeth.1250

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