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Synergistic effect of human CycT1 and CRM1 on HIV-1 propagation in rat T cells and macrophages
BACKGROUND: In vivo studies of HIV-1 pathogenesis and testing of antiviral strategies have been hampered by the lack of an immunocompetent small animal model that is highly susceptible to HIV-1 infection. Although transgenic rats that express the HIV-1 receptor complex hCD4 and hCCR5 are susceptible...
Autores principales: | Okada, Hiroyuki, Zhang, Xianfeng, Ben Fofana, Ismael, Nagai, Mika, Suzuki, Hajime, Ohashi, Takashi, Shida, Hisatoshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693497/ https://www.ncbi.nlm.nih.gov/pubmed/19435492 http://dx.doi.org/10.1186/1742-4690-6-43 |
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