Structural Basis for Self-Renewal of Neural Progenitors in Cortical Neurogenesis

In mammalian brain development, neuroepithelial cells act as progenitors that produce self-renewing and differentiating cells. Recent technical advances in live imaging and gene manipulation now enable us to investigate how neural progenitors generate the 2 different types of cells with unprecedente...

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Detalles Bibliográficos
Autores principales: Shioi, Go, Konno, Daijiro, Shitamukai, Atsunori, Matsuzaki, Fumio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693538/
https://www.ncbi.nlm.nih.gov/pubmed/19363147
http://dx.doi.org/10.1093/cercor/bhp042
Descripción
Sumario:In mammalian brain development, neuroepithelial cells act as progenitors that produce self-renewing and differentiating cells. Recent technical advances in live imaging and gene manipulation now enable us to investigate how neural progenitors generate the 2 different types of cells with unprecedented accuracy and resolution, shedding new light on the roles of epithelial structure in cell fate decisions and also on the plasticity of neurogenesis.

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