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Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center
This study was to investigate clinical characteristics and any differential trends in survival among renal replacement therapy (hemodialysis [HD], peritoneal dialysis [PD], and kidney transplantation [KT]) in Korean end-stage renal disease (ESRD) population. We tried to analyze retrospectively the s...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693574/ https://www.ncbi.nlm.nih.gov/pubmed/17297256 http://dx.doi.org/10.3346/jkms.2007.22.1.81 |
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author | Song, Young-Soo Jung, Heesun Shim, Jinyoung Oh, Changkwon Shin, Gyu-Tae Kim, Heungsoo |
author_facet | Song, Young-Soo Jung, Heesun Shim, Jinyoung Oh, Changkwon Shin, Gyu-Tae Kim, Heungsoo |
author_sort | Song, Young-Soo |
collection | PubMed |
description | This study was to investigate clinical characteristics and any differential trends in survival among renal replacement therapy (hemodialysis [HD], peritoneal dialysis [PD], and kidney transplantation [KT]) in Korean end-stage renal disease (ESRD) population. We tried to analyze retrospectively the survival rate adjusted by risk factors and the relative risk stratified by key risk factors among 447 ESRD patients who began dialysis or had a kidney transplant at Ajou University Hospital from 1994 to 2004. In adjusted Cox survival curves, the KT patients had the best survival rate, and the HD patients had better survival than PD patients. The consistent trends in different subgroups stratified by age and diabetes were as following: 1) The risk of death for PD and HD was not proportional over time, 2) The relative risk of PD was similar or lower than that of HD for the first 12 months, but it became higher at later period. The significant predictors for mortality were age (over 55 yr), presence of diabetes, cerebrovascular accident at ESRD onset, and more than one time of hospitalization caused by malnutrition. Further large-scaled, multicenter-based comparative study is needed in Korean ESRD patients and more meticulous attention is required in high-risk patients. |
format | Text |
id | pubmed-2693574 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-26935742009-06-11 Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center Song, Young-Soo Jung, Heesun Shim, Jinyoung Oh, Changkwon Shin, Gyu-Tae Kim, Heungsoo J Korean Med Sci Original Article This study was to investigate clinical characteristics and any differential trends in survival among renal replacement therapy (hemodialysis [HD], peritoneal dialysis [PD], and kidney transplantation [KT]) in Korean end-stage renal disease (ESRD) population. We tried to analyze retrospectively the survival rate adjusted by risk factors and the relative risk stratified by key risk factors among 447 ESRD patients who began dialysis or had a kidney transplant at Ajou University Hospital from 1994 to 2004. In adjusted Cox survival curves, the KT patients had the best survival rate, and the HD patients had better survival than PD patients. The consistent trends in different subgroups stratified by age and diabetes were as following: 1) The risk of death for PD and HD was not proportional over time, 2) The relative risk of PD was similar or lower than that of HD for the first 12 months, but it became higher at later period. The significant predictors for mortality were age (over 55 yr), presence of diabetes, cerebrovascular accident at ESRD onset, and more than one time of hospitalization caused by malnutrition. Further large-scaled, multicenter-based comparative study is needed in Korean ESRD patients and more meticulous attention is required in high-risk patients. The Korean Academy of Medical Sciences 2007-02 2007-02-28 /pmc/articles/PMC2693574/ /pubmed/17297256 http://dx.doi.org/10.3346/jkms.2007.22.1.81 Text en Copyright © 2007 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Song, Young-Soo Jung, Heesun Shim, Jinyoung Oh, Changkwon Shin, Gyu-Tae Kim, Heungsoo Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center |
title | Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center |
title_full | Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center |
title_fullStr | Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center |
title_full_unstemmed | Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center |
title_short | Survival Analysis of Korean End-Stage Renal Disease Patients According to Renal Replacement Therapy in a Single Center |
title_sort | survival analysis of korean end-stage renal disease patients according to renal replacement therapy in a single center |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693574/ https://www.ncbi.nlm.nih.gov/pubmed/17297256 http://dx.doi.org/10.3346/jkms.2007.22.1.81 |
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