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A Computational Model of Aging and Calcification in the Aortic Heart Valve
The aortic heart valve undergoes geometric and mechanical changes over time. The cusps of a normal, healthy valve thicken and become less extensible over time. In the disease calcific aortic stenosis (CAS), calcified nodules progressively stiffen the cusps. The local mechanical changes in the cusps,...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693668/ https://www.ncbi.nlm.nih.gov/pubmed/19536285 http://dx.doi.org/10.1371/journal.pone.0005960 |