Cargando…
Sulfonylurea Therapy in Two Korean Patients with Insulin-treated Neonatal Diabetes due to Heterozygous Mutations of the KCNJ11 Gene Encoding Kir6.2
Permanent neonatal diabetes (PND) is a rare form of diabetes characterized by insulin-requiring hyperglycemia diagnosed within the first three months of life. In most cases, the causes are not known. Recently, mutations in the KCNJ11 gene encoding the Kir6.2 subunit of the ATP-sensitive K(+) channel...
Autores principales: | Kim, Min Sun, Kim, Sun-Young, Kim, Gu-Hwan, Yoo, Han Wook, Lee, Dong Whan, Lee, Dae-Yeol |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693808/ https://www.ncbi.nlm.nih.gov/pubmed/17728498 http://dx.doi.org/10.3346/jkms.2007.22.4.616 |
Ejemplares similares
-
DEND Syndrome with Heterozygous KCNJ11 Mutation Successfully Treated with Sulfonylurea
por: Cho, Ja Hyang, et al.
Publicado: (2017) -
Successful sulfonylurea treatment in a patient with permanent neonatal diabetes mellitus with a novel KCNJ11 mutation
por: Ahn, Sung Yeon, et al.
Publicado: (2015) -
Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes
por: Babiker, Tarig, et al.
Publicado: (2016) -
Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A K(ATP) channels: A mechanistic study
por: Proks, Peter, et al.
Publicado: (2014) -
Congenital Hyperinsulinism and Glucose Hypersensitivity in Homozygous and Heterozygous Carriers of Kir6.2 (KCNJ11) Mutation V290M Mutation: K(ATP) Channel Inactivation Mechanism and Clinical Management
por: Loechner, Karen J., et al.
Publicado: (2011)