3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases

Eukaryotic DNA replication requires the coordinated activity of the multi-subunit DNA polymerases: Pol α, Pol δ and Pol ɛ. The conserved catalytic and regulatory B subunits associate in a constitutive heterodimer that represents the functional core of all three replicative polymerases. Here, we comb...

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Detalles Bibliográficos
Autores principales: Klinge, Sebastian, Núñez-Ramírez, Rafael, Llorca, Oscar, Pellegrini, Luca
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693882/
https://www.ncbi.nlm.nih.gov/pubmed/19494830
http://dx.doi.org/10.1038/emboj.2009.150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693882/
https://www.ncbi.nlm.nih.gov/pubmed/19494830
http://dx.doi.org/10.1038/emboj.2009.150

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