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3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases
Eukaryotic DNA replication requires the coordinated activity of the multi-subunit DNA polymerases: Pol α, Pol δ and Pol ɛ. The conserved catalytic and regulatory B subunits associate in a constitutive heterodimer that represents the functional core of all three replicative polymerases. Here, we comb...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693882/ https://www.ncbi.nlm.nih.gov/pubmed/19494830 http://dx.doi.org/10.1038/emboj.2009.150 |