Cargando…

A Functional γδTCR/CD3 Complex Distinct from γδT Cells Is Expressed by Human Eosinophils

BACKGROUND: Eosinophils are effector cells during parasitic infections and allergic responses. However, their contribution to innate immunity has been only recently unravelled. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that human eosinophils express CD3 and γδ T Cell Receptor (TCR) but not αβ TCR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Legrand, Fanny, Driss, Virginie, Woerly, Gaëtane, Loiseau, Sylvie, Hermann, Emmanuel, Fournié, Jean-Jacques, Héliot, Laurent, Mattot, Virginie, Soncin, Fabrice, Gougeon, Marie-Lise, Dombrowicz, David, Capron, Monique
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693924/ https://www.ncbi.nlm.nih.gov/pubmed/19536290 http://dx.doi.org/10.1371/journal.pone.0005926

Ejemplares similares

Expression of Cd28 and Cd86 by Human Eosinophils and Role in the Secretion of Type 1 Cytokines (Interleukin 2 and Interferon γ): Inhibition by Immunoglobulin a Complexes
por: Woerly, Gaëtane, et al.
Publicado: (1999)

Peroxisome Proliferator–activated Receptors α and γ Down-regulate Allergic Inflammation and Eosinophil Activation
por: Woerly, Gaetane, et al.
Publicado: (2003)

Spleen tyrosine kinase mediates the γδTCR signaling required for γδT cell commitment and γδT17 differentiation
por: Muro, Ryunosuke, et al.
Publicado: (2023)

Human γδ TCR Repertoires in Health and Disease
por: Fichtner, Alina Suzann, et al.
Publicado: (2020)

Identification of the Ligands of TCRγδ by Screening the Immune Repertoire of γδT Cells From Patients With Tuberculosis
por: Li, Yuxia, et al.
Publicado: (2019)

Premature Expression of T Cell Receptor (Tcr)αβ Suppresses Tcrγδ Gene Rearrangement but Permits Development of γδ Lineage T Cells
por: Terrence, Kathleen, et al.
Publicado: (2000)

Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells
por: Sumaria, Nital, et al.
Publicado: (2017)

Selective activation of TCR-γδ(+ )cells in endemic Burkitt's lymphoma
por: Futagbi, Godfred, et al.
Publicado: (2007)

Egfl7 Is Differentially Expressed in Arteries and Veins during Retinal Vascular Development
por: Poissonnier, Loïc, et al.
Publicado: (2014)

γδ TCR Recognition of MR1: Adapting to Life on the Flip Side
por: Willcox, Benjamin E., et al.
Publicado: (2020)

Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions
por: Deseke, Malte, et al.
Publicado: (2020)

γδ TCR T lymphoblastic leukemia in a child presenting with marked hyperleukocytosis
por: Mass, Jirong, et al.
Publicado: (2021)

Defining TCRγδ lymphoproliferative disorders by combined immunophenotypic and molecular evaluation
por: Teramo, Antonella, et al.
Publicado: (2022)

Lymph act, TCR αβ, TCR γδ cells in peripheral blood in children with juvenile idiopathic arthritis
por: Mazur-Zielinska, H
Publicado: (2008)

γδ T Lymphocytes Coordinate Eosinophil Influx during Allergic Responses
por: de Oliveira Henriques, Maria Das Graças Muller, et al.
Publicado: (2012)

GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR
por: Straetemans, Trudy, et al.
Publicado: (2018)

γδTCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis
por: Bouchareychas, Laura, et al.
Publicado: (2018)

The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy
por: Legut, Mateusz, et al.
Publicado: (2015)

Plasticity of γδ T Cells: Impact on the Anti-Tumor Response
por: Lafont, Virginie, et al.
Publicado: (2014)

Roles of the Src Tyrosine Kinases Lck and Fyn in Regulating γδTCR Signal Strength
por: Laird, Renee M., et al.
Publicado: (2010)

Phosphoantigen Presentation to TCR γδ Cells, a Conundrum Getting Less Gray Zones
por: De Libero, Gennaro, et al.
Publicado: (2015)

TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets
por: Muñoz-Ruiz, Miguel, et al.
Publicado: (2016)

Quantitative B-lymphocyte deficiency and increased TCRγδ T-lymphocytes in acute infectious spondylodiscitis
por: Haugaard, Anna K., et al.
Publicado: (2018)

Interleukin‐17‐producing γδ T (γδ17) cells in inflammatory diseases
por: Akitsu, Aoi, et al.
Publicado: (2018)

The Aging of γδ T Cells
por: Xu, Weili, et al.
Publicado: (2020)

A Novel Strategy to Screen Bacillus Calmette-Guérin Protein Antigen Recognized by γδ TCR
por: Xi, XueYan, et al.
Publicado: (2011)

Aberrant Loss of Surface CD3 and TCRγδ Expression in Relapsed Hepatosplenic T-cell Lymphoma
por: Lee, Beomki, et al.
Publicado: (2021)

TGF-β controls development of TCRγδ(+)CD8αα(+) intestinal intraepithelial lymphocytes
por: Han, Jiajia, et al.
Publicado: (2023)

The Distinct Contributions of Murine T Cell Receptor (TCR)γδ(+) and TCRαβ(+) T Cells to Different Stages of Chemically Induced Skin Cancer
por: Girardi, Michael, et al.
Publicado: (2003)

Diversity of Tumor-Infiltrating, γδ T-Cell Abundance in Solid Cancers
por: Chabab, Ghita, et al.
Publicado: (2020)

Pro-tumor γδ T Cells in Human Cancer: Polarization, Mechanisms of Action, and Implications for Therapy
por: Chabab, Ghita, et al.
Publicado: (2020)

Monitoring Circulating γδ T Cells in Cancer Patients to Optimize γδ T Cell-Based Immunotherapy
por: Oberg, Hans-Heinrich, et al.
Publicado: (2014)

Imbalance of γδT17/γδTreg cells in the pathogenesis of allergic asthma induced by ovalbumin
por: Yang, Xia, et al.
Publicado: (2018)

Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity
por: Gully, Benjamin S., et al.
Publicado: (2021)

γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function
por: Tao, Changli, et al.
Publicado: (2017)

Dysregulated signaling, proliferation and apoptosis impact on the pathogenesis of TCRγδ+ T cell large granular lymphocyte leukemia
por: Kallemeijn, Martine J., et al.
Publicado: (2017)

Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin’s lymphoma
por: Muller, Christina K. S., et al.
Publicado: (2021)

Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control
por: Johanna, Inez, et al.
Publicado: (2021)

Clinicopathological Correlates of γδ T Cell Infiltration in Triple-Negative Breast Cancer
por: Boissière-Michot, Florence, et al.
Publicado: (2021)

γδ T cells take on CMV
por: Van Epps, Heather L.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_omtue59hj5vgddi3n6u0ldmnom