Oxidative cyclization of alkenols with Oxone using a miniflow reactor

A miniflow system for oxidative cyclization of alkenols with Oxone was developed. Thus, the oxidative cyclization of (Z)- and (E)-alkenols in i-PrOH with an aqueous solution of Oxone proceeded smoothly and safely in a PTFE tube without any exogenous catalytic species, and was subsequently quenched i...

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Detalles Bibliográficos
Autores principales: Yamada, Yoichi M A, Torii, Kaoru, Uozumi, Yasuhiro
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2009
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693950/
https://www.ncbi.nlm.nih.gov/pubmed/19513188
http://dx.doi.org/10.3762/bjoc.5.18
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author Yamada, Yoichi M A
Torii, Kaoru
Uozumi, Yasuhiro
author_facet Yamada, Yoichi M A
Torii, Kaoru
Uozumi, Yasuhiro
author_sort Yamada, Yoichi M A
collection PubMed
description A miniflow system for oxidative cyclization of alkenols with Oxone was developed. Thus, the oxidative cyclization of (Z)- and (E)-alkenols in i-PrOH with an aqueous solution of Oxone proceeded smoothly and safely in a PTFE tube without any exogenous catalytic species, and was subsequently quenched in a flow-reaction manner to afford the corresponding furanyl and pyranyl carbinols quantitatively within 5 or 10 min of residence time.
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spelling pubmed-26939502009-06-09 Oxidative cyclization of alkenols with Oxone using a miniflow reactor Yamada, Yoichi M A Torii, Kaoru Uozumi, Yasuhiro Beilstein J Org Chem Preliminary Communication A miniflow system for oxidative cyclization of alkenols with Oxone was developed. Thus, the oxidative cyclization of (Z)- and (E)-alkenols in i-PrOH with an aqueous solution of Oxone proceeded smoothly and safely in a PTFE tube without any exogenous catalytic species, and was subsequently quenched in a flow-reaction manner to afford the corresponding furanyl and pyranyl carbinols quantitatively within 5 or 10 min of residence time. Beilstein-Institut 2009-04-29 /pmc/articles/PMC2693950/ /pubmed/19513188 http://dx.doi.org/10.3762/bjoc.5.18 Text en Copyright © 2009, Yamada et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Preliminary Communication
Yamada, Yoichi M A
Torii, Kaoru
Uozumi, Yasuhiro
Oxidative cyclization of alkenols with Oxone using a miniflow reactor
title Oxidative cyclization of alkenols with Oxone using a miniflow reactor
title_full Oxidative cyclization of alkenols with Oxone using a miniflow reactor
title_fullStr Oxidative cyclization of alkenols with Oxone using a miniflow reactor
title_full_unstemmed Oxidative cyclization of alkenols with Oxone using a miniflow reactor
title_short Oxidative cyclization of alkenols with Oxone using a miniflow reactor
title_sort oxidative cyclization of alkenols with oxone using a miniflow reactor
topic Preliminary Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693950/
https://www.ncbi.nlm.nih.gov/pubmed/19513188
http://dx.doi.org/10.3762/bjoc.5.18
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AT toriikaoru oxidativecyclizationofalkenolswithoxoneusingaminiflowreactor
AT uozumiyasuhiro oxidativecyclizationofalkenolswithoxoneusingaminiflowreactor

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