Conjunctival-corneal melt in association with carotid artery stenosis

PURPOSE: To report a case of severe conjunctival-corneal melt in association with carotid artery stenosis. METHODS: Observational case report. RESULTS: A 76-year-old man with a history of bilateral severe carotid artery occlusion and nonarteritic ischemic optic neuropathy developed a spontaneous bul...

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Detalles Bibliográficos
Autores principales: Stewart, Rosalind MK, Quah, Say Aun, Nguyen, Dan Q, Kaye, Stephen B
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694008/
https://www.ncbi.nlm.nih.gov/pubmed/19668768
Descripción
Sumario:PURPOSE: To report a case of severe conjunctival-corneal melt in association with carotid artery stenosis. METHODS: Observational case report. RESULTS: A 76-year-old man with a history of bilateral severe carotid artery occlusion and nonarteritic ischemic optic neuropathy developed a spontaneous bulbar conjunctival defect. Despite intensive lubrication, and attempts at surgical closure including an amniotic membrane patch graft, it progressed with subsequent adjacent corneal perforation. Thorough investigations revealed no underlying disease, except markedly delayed episcleral vessel filling on anterior segment fluorescein angiography. CONCLUSIONS: Neovascularisation is a known factor in the inhibition of ulceration. In light of the findings in this report, ocular ischemia should be considered as a cause or contributing factor in the differential diagnosis of conjunctival-corneal melt.

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