Cargando…

Alpha6beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer

BACKGROUND: The α6β4 integrin is overexpressed in the basal subtype of breast cancer and plays an important role in tumor cell motility and invasion. EGFR is also overexpressed in the basal subtype of breast cancer, and crosstalk between α6β4 integrin and EGFR appears to be important in tumor progre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gilcrease, Michael Z, Zhou, Xiao, Lu, Xiaolin, Woodward, Wendy A, Hall, Brian E, Morrissey, Phillip J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694164/ https://www.ncbi.nlm.nih.gov/pubmed/19470173 http://dx.doi.org/10.1186/1756-9966-28-67

Ejemplares similares

The intracellular functions of alpha6beta4 integrin are regulated by EGF
Publicado: (1996)

CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells
por: Deng, Wenjie, et al.
Publicado: (2016)

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering
Publicado: (1992)

Critical roles for EGFR and EGFR–HER2 clusters in EGF binding of SW620 human carcinoma cells
por: Wollman, Adam J. M., et al.
Publicado: (2022)

The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1
Publicado: (1995)

Integrin beta 3 cytoplasmic tail is necessary and sufficient for regulation of alpha 5 beta 1 phagocytosis by alpha v beta 3 and integrin-associated protein
Publicado: (1995)

β3 Integrin–EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells
por: Balanis, Nikolas, et al.
Publicado: (2011)

Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway
por: Sheng, Weiwei, et al.
Publicado: (2017)

Genetic variations in EGF and EGFR and glioblastoma outcome
por: Sjöström, Sara, et al.
Publicado: (2010)

The integrin alpha 6 beta 4 is a laminin receptor
Publicado: (1992)

Selective toxicity of TGF-alpha-PE40 to EGFR-positive cell lines: selective protection of low EGFR-expressing cell lines by EGF.
por: Kirk, J., et al.
Publicado: (1994)

Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites
Publicado: (1995)

Rho Gtpases: Integrating Integrin Signaling
por: Ridley, Anne
Publicado: (2000)

Role of alpha 2 beta 1- and alpha 3 beta 1-integrin in the peritoneal implantation of scirrhous gastric carcinoma.
por: Nishimura, S., et al.
Publicado: (1996)

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4
Publicado: (1990)

Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion
Publicado: (1993)

EGF Functionalized Polymer-Coated Gold Nanoparticles Promote EGF Photostability and EGFR Internalization for Photothermal Therapy
por: Silva, Catarina Oliveira, et al.
Publicado: (2016)

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro
Publicado: (1990)

Alpha2beta1 Integrin Polymorphism in Diffuse Astrocytoma Patients
por: Teixeira, Silvia A., et al.
Publicado: (2022)

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1
Publicado: (1994)

The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin
Publicado: (1990)

Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction
por: Li, Xueke, et al.
Publicado: (2022)

$B \to \rho \pi, B \to \rho \rho$ and the measurement of $\alpha$ at LHCb
por: Robbe, Patrick
Publicado: (2006)

RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer
por: Di Donato, Marzia, et al.
Publicado: (2023)

Polarized expression of integrin receptors (alpha 6 beta 4, alpha 2 beta 1, alpha 3 beta 1, and alpha v beta 5) and their relationship with the cytoskeleton and basement membrane matrix in cultured human keratinocytes
Publicado: (1991)

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface
Publicado: (1991)

Abnormal expression of integrin alpha 6 beta 4 in cervical intraepithelial neoplasia.
por: Aplin, J. D., et al.
Publicado: (1996)

Alpha6beta1 integrin expressed by sperm is determinant in mouse fertilization
por: Barraud-Lange, Virginie, et al.
Publicado: (2007)

In vivo alpha-V beta-3 integrin expression in human aortic atherosclerosis
por: Jenkins, William S, et al.
Publicado: (2019)

The anchorage-dependent and -independent growth of a human SCC cell line: the roles of TGF alpha/EGF and TGF beta.
por: McLeod, C., et al.
Publicado: (1990)

The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells
Publicado: (1990)

Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis
Publicado: (1996)

Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin
Publicado: (1995)

Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit
Publicado: (1993)

The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment
por: Huang, Peixin, et al.
Publicado: (2014)

Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation
por: Zheng, Jianchao, et al.
Publicado: (2017)

HCC-derived EGFR mutants are functioning, EGF-dependent, and erlotinib-resistant
por: Sueangoen, Natthaporn, et al.
Publicado: (2020)

Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor
Publicado: (1989)

Thrombospondin modulates alpha v beta 3 function through integrin- associated protein
Publicado: (1996)

$B^0 \to \rho \pi , B^0 \to \rho \rho$ and the measurement of $\alpha$ at LHCb
por: Robbe, Patrick
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_djip6hncfmcak6bl98eivj8uk9