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Complex Segregation Analysis of Pedigrees from the Gilda Radner Familial Ovarian Cancer Registry Reveals Evidence for Mendelian Dominant Inheritance

BACKGROUND: Familial component is estimated to account for about 10% of ovarian cancer. However, the mode of inheritance of ovarian cancer remains poorly understood. The goal of this study was to investigate the inheritance model that best fits the observed transmission pattern of ovarian cancer amo...

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Detalles Bibliográficos
Autores principales:	Tayo, Bamidele O., DiCioccio, Richard A., Liang, Yulan, Trevisan, Maurizio, Cooper, Richard S., Lele, Shashikant, Sucheston, Lara, Piver, Steven M., Odunsi, Kunle
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694280/ https://www.ncbi.nlm.nih.gov/pubmed/19536330 http://dx.doi.org/10.1371/journal.pone.0005939

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