A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease

A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves' disease was described. The patient was treated with Lugol's solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and s...

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Detalles Bibliográficos
Autores principales: Seo, Je Hyun, Yu, Hyeong Gon, Chung, Hum
Formato: Texto
Lenguaje:English
Publicado: The Korean Ophthalmological Society 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694287/
https://www.ncbi.nlm.nih.gov/pubmed/19568361
http://dx.doi.org/10.3341/kjo.2009.23.2.112
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author Seo, Je Hyun
Yu, Hyeong Gon
Chung, Hum
author_facet Seo, Je Hyun
Yu, Hyeong Gon
Chung, Hum
author_sort Seo, Je Hyun
collection PubMed
description A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves' disease was described. The patient was treated with Lugol's solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and steroid-induced myopathy. Fluorescein angiography showed multiple leakage points and a lumbar puncture revealed pleocytosis, which was compatible with VKH. High dose steroid pulse therapy was successful. Altered immune regulation associated with drug-induced hypersensitivity may contribute to the development of VKH in patients with Graves' disease.
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spelling pubmed-26942872009-07-01 A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease Seo, Je Hyun Yu, Hyeong Gon Chung, Hum Korean J Ophthalmol Case Report A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves' disease was described. The patient was treated with Lugol's solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and steroid-induced myopathy. Fluorescein angiography showed multiple leakage points and a lumbar puncture revealed pleocytosis, which was compatible with VKH. High dose steroid pulse therapy was successful. Altered immune regulation associated with drug-induced hypersensitivity may contribute to the development of VKH in patients with Graves' disease. The Korean Ophthalmological Society 2009-06 2009-06-09 /pmc/articles/PMC2694287/ /pubmed/19568361 http://dx.doi.org/10.3341/kjo.2009.23.2.112 Text en Copyright © 2009 by the Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Seo, Je Hyun
Yu, Hyeong Gon
Chung, Hum
A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
title A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
title_full A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
title_fullStr A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
title_full_unstemmed A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
title_short A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
title_sort case of vogt-koyanagi-harada disease in a patient with graves disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694287/
https://www.ncbi.nlm.nih.gov/pubmed/19568361
http://dx.doi.org/10.3341/kjo.2009.23.2.112
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