Cargando…

Divergent Cardiopulmonary Actions of Heme Oxygenase Enzymatic Products in Chronic Hypoxia

BACKGROUND: Hypoxia and pressure-overload induce heme oxygenase-1 (HO-1) in cardiomyocytes and vascular smooth muscle cells (VSMCs). HO-1(−/−) mice exposed to chronic hypoxia develop pulmonary arterial hypertension (PAH) with exaggerated right ventricular (RV) injury consisting of dilation, fibrosis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vitali, Sally H., Mitsialis, S. Alex, Liang, Olin D., Liu, Xiaoli, Fernandez-Gonzalez, Angeles, Christou, Helen, Wu, Xinqi, McGowan, Francis X., Kourembanas, Stella
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694354/ https://www.ncbi.nlm.nih.gov/pubmed/19543386 http://dx.doi.org/10.1371/journal.pone.0005978

Ejemplares similares

Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension
por: Hansmann, Georg, et al.
Publicado: (2012)

‘Good things come in small packages’: Application of exosome-based therapeutics in neonatal lung injury
por: Willis, Gareth R, et al.
Publicado: (2017)

Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency
por: Willis, Gareth R., et al.
Publicado: (2017)

Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension?
por: Willis, Gareth R., et al.
Publicado: (2018)

Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia
por: Tift, Michael S., et al.
Publicado: (2020)

Anti-apoptosis effect of heme oxygenase-1 on lung injury after cardiopulmonary bypass
por: Sheng, Wei, et al.
Publicado: (2020)

The Role of Heme Oxygenase-1 as an Immunomodulator in Kidney Disease
por: Athanassiadou, Virginia, et al.
Publicado: (2022)

Heme Oxygenase-1 Deficiency
por: Renji, Soumya, et al.
Publicado: (2021)

Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective
por: Fernandez-Gonzalez, Angeles, et al.
Publicado: (2021)

Paving the Road for Mesenchymal Stem Cell-Derived Exosome Therapy in Bronchopulmonary Dysplasia and Pulmonary Hypertension
por: Yeung, Vincent, et al.
Publicado: (2019)

Role of Heme Oxygenase as a Modulator of Heme-Mediated Pathways
por: Duvigneau, J. Catharina, et al.
Publicado: (2019)

Heme-heme oxygenase-2 reduces the atherosclerosis by preventing inflammation
por: Wang, Zhenzhen, et al.
Publicado: (2022)

Peroxynitrite-mediated inactivation of heme oxygenases
por: Kinobe, Robert, et al.
Publicado: (2004)

Heme oxygenase 1 regulates osteoclastogenesis
por: Zwerina, J, et al.
Publicado: (2005)

Curcumin and Heme Oxygenase: Neuroprotection and Beyond
por: Mhillaj, Emanuela, et al.
Publicado: (2019)

The non-canonical functions of the heme oxygenases
por: Vanella, Luca, et al.
Publicado: (2016)

Integrative Survival Response Evoked by Heme Oxygenase-1 and Heme Metabolites
por: Pae, Hyun-Ock, et al.
Publicado: (2008)

How Heme Oxygenase-1 Prevents Heme-Induced Cell Death
por: Lanceta, Lilibeth, et al.
Publicado: (2015)

A noncanonical heme oxygenase specific for the degradation of c-type heme
por: Li, Shuxin, et al.
Publicado: (2021)

Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2
por: Stevenson, David K., et al.
Publicado: (2023)

Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension
por: Spyropoulos, Fotios, et al.
Publicado: (2021)

Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1
por: Son, Yong, et al.
Publicado: (2013)

Heme Oxygenase-1, Oxidation, Inflammation, and Atherosclerosis
por: Araujo, Jesus A., et al.
Publicado: (2012)

The Expression of Heme Oxygenase-1 Induced by Lansoprazole
por: Takagi, Tomohisa, et al.
Publicado: (2009)

Pharmacological Targeting of Heme Oxygenase-1 in Osteoarthritis
por: Sanada, Yohei, et al.
Publicado: (2021)

Pharmacological and Clinical Significance of Heme Oxygenase-1
por: Stec, David E., et al.
Publicado: (2021)

Role of Heme Oxygenase in Gastrointestinal Epithelial Cells
por: Akagi, Reiko
Publicado: (2022)

The roles of heme oxygenase-1 in renal disease
por: Zhai, Hongfu, et al.
Publicado: (2023)

Immune-Related Functions of Heme Oxygenase-1
por: Lianos, Elias A., et al.
Publicado: (2023)

Echocardiographic markers of pulmonary hemodynamics and right ventricular hypertrophy in rat models of pulmonary hypertension
por: Spyropoulos, Fotios, et al.
Publicado: (2020)

Heme Oxygenase Isoforms Differ in Their Subcellular Trafficking during Hypoxia and Are Differentially Modulated by Cytochrome P450 Reductase
por: Linnenbaum, Monika, et al.
Publicado: (2012)

Induction of Peroxiredoxin 1 by Hypoxia Regulates Heme Oxygenase-1 via NF-κB in Oral Cancer
por: Zhang, Min, et al.
Publicado: (2014)

Hypoxia‐induced oxidative stress promotes therapy resistance via upregulation of heme oxygenase‐1 in multiple myeloma
por: Abe, Ko, et al.
Publicado: (2023)

Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice
por: Suttorp, Christiaan M., et al.
Publicado: (2020)

Heme Oxygenase-1 Deletion Affects Stress Erythropoiesis
por: Cao, Yu-An, et al.
Publicado: (2011)

Heme Oxygenase, Inflammation, and Fibrosis: The Good, the Bad, and the Ugly?
por: Lundvig, Ditte M. S., et al.
Publicado: (2012)

Novel Insights into the Vasoprotective Role of Heme Oxygenase-1
por: Marcantoni, Emanuela, et al.
Publicado: (2012)

Heme oxygenase-1 and carbon monoxide in pulmonary medicine
por: Slebos, Dirk-Jan, et al.
Publicado: (2003)

Heme Oxygenase-1 as a Novel Metabolic Player
por: Chung, Hun-Taeg, et al.
Publicado: (2013)

Heme oxygenase and the immune system in normal and pathological pregnancies
por: Ozen, Maide, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qfcref88m8feg97qtkvuigp7rc