Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key disease genes within them, but also the biological relationships among those key genes. Here we describe a statistical method, Gene Relationships Among Implicated Loci (GRA...

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Detalles Bibliográficos
Autores principales: Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth J., Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward M., Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694358/
https://www.ncbi.nlm.nih.gov/pubmed/19557189
http://dx.doi.org/10.1371/journal.pgen.1000534

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