Epigenetic Silencing of Host Cell Defense Genes Enhances Intracellular Survival of the Rickettsial Pathogen Anaplasma phagocytophilum

Intracellular bacteria have evolved mechanisms that promote survival within hostile host environments, often resulting in functional dysregulation and disease. Using the Anaplasma phagocytophilum–infected granulocyte model, we establish a link between host chromatin modifications, defense gene trans...

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Detalles Bibliográficos
Autores principales: Garcia-Garcia, Jose C., Barat, Nicole C., Trembley, Sarah J., Dumler, J. Stephen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694362/
https://www.ncbi.nlm.nih.gov/pubmed/19543390
http://dx.doi.org/10.1371/journal.ppat.1000488

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