Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man

Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a pri...

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Autores principales: Lee, Yoon Young, Kim, Do Hoon, Lee, Ji Hye, Choi, Jong Sang, In, Kwang Ho, Oh, Yu Whan, Cho, Kyung Hwan, Roh, Yong Kyun
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694395/
https://www.ncbi.nlm.nih.gov/pubmed/17923745
http://dx.doi.org/10.3346/jkms.2007.22.S.S159
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author Lee, Yoon Young
Kim, Do Hoon
Lee, Ji Hye
Choi, Jong Sang
In, Kwang Ho
Oh, Yu Whan
Cho, Kyung Hwan
Roh, Yong Kyun
author_facet Lee, Yoon Young
Kim, Do Hoon
Lee, Ji Hye
Choi, Jong Sang
In, Kwang Ho
Oh, Yu Whan
Cho, Kyung Hwan
Roh, Yong Kyun
author_sort Lee, Yoon Young
collection PubMed
description Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a primary pulmonary origin. The mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 22q12 rearrangement. The diagnosis was confirmed both pathologically and genetically. The mass lesion was resected, and the patient is currently undergoing chemotherapy.
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spelling pubmed-26943952009-06-11 Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man Lee, Yoon Young Kim, Do Hoon Lee, Ji Hye Choi, Jong Sang In, Kwang Ho Oh, Yu Whan Cho, Kyung Hwan Roh, Yong Kyun J Korean Med Sci Case Report Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a primary pulmonary origin. The mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 22q12 rearrangement. The diagnosis was confirmed both pathologically and genetically. The mass lesion was resected, and the patient is currently undergoing chemotherapy. The Korean Academy of Medical Sciences 2007-09 2007-09-30 /pmc/articles/PMC2694395/ /pubmed/17923745 http://dx.doi.org/10.3346/jkms.2007.22.S.S159 Text en Copyright © 2007 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Yoon Young
Kim, Do Hoon
Lee, Ji Hye
Choi, Jong Sang
In, Kwang Ho
Oh, Yu Whan
Cho, Kyung Hwan
Roh, Yong Kyun
Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
title Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
title_full Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
title_fullStr Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
title_full_unstemmed Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
title_short Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
title_sort primary pulmonary ewing's sarcoma/primitive neuroectodermal tumor in a 67-year-old man
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694395/
https://www.ncbi.nlm.nih.gov/pubmed/17923745
http://dx.doi.org/10.3346/jkms.2007.22.S.S159
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