Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man
Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a pri...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694395/ https://www.ncbi.nlm.nih.gov/pubmed/17923745 http://dx.doi.org/10.3346/jkms.2007.22.S.S159 |
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author | Lee, Yoon Young Kim, Do Hoon Lee, Ji Hye Choi, Jong Sang In, Kwang Ho Oh, Yu Whan Cho, Kyung Hwan Roh, Yong Kyun |
author_facet | Lee, Yoon Young Kim, Do Hoon Lee, Ji Hye Choi, Jong Sang In, Kwang Ho Oh, Yu Whan Cho, Kyung Hwan Roh, Yong Kyun |
author_sort | Lee, Yoon Young |
collection | PubMed |
description | Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a primary pulmonary origin. The mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 22q12 rearrangement. The diagnosis was confirmed both pathologically and genetically. The mass lesion was resected, and the patient is currently undergoing chemotherapy. |
format | Text |
id | pubmed-2694395 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-26943952009-06-11 Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man Lee, Yoon Young Kim, Do Hoon Lee, Ji Hye Choi, Jong Sang In, Kwang Ho Oh, Yu Whan Cho, Kyung Hwan Roh, Yong Kyun J Korean Med Sci Case Report Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a primary pulmonary origin. The mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 22q12 rearrangement. The diagnosis was confirmed both pathologically and genetically. The mass lesion was resected, and the patient is currently undergoing chemotherapy. The Korean Academy of Medical Sciences 2007-09 2007-09-30 /pmc/articles/PMC2694395/ /pubmed/17923745 http://dx.doi.org/10.3346/jkms.2007.22.S.S159 Text en Copyright © 2007 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lee, Yoon Young Kim, Do Hoon Lee, Ji Hye Choi, Jong Sang In, Kwang Ho Oh, Yu Whan Cho, Kyung Hwan Roh, Yong Kyun Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man |
title | Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man |
title_full | Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man |
title_fullStr | Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man |
title_full_unstemmed | Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man |
title_short | Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man |
title_sort | primary pulmonary ewing's sarcoma/primitive neuroectodermal tumor in a 67-year-old man |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694395/ https://www.ncbi.nlm.nih.gov/pubmed/17923745 http://dx.doi.org/10.3346/jkms.2007.22.S.S159 |
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