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Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis on binding to its receptors, death receptor 4 and 5 (DR4, DR5). TRAIL can also activate c-Jun N-terminal kinase (JNK) through the adaptor molecules, TNF receptor-associated factor 2 (TRAF2) and receptor-interacting pr...

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Detalles Bibliográficos
Autores principales:	Mahalingam, D, Keane, M, Pirianov, G, Mehmet, H, Samali, A, Szegezdi, E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694422/ https://www.ncbi.nlm.nih.gov/pubmed/19352384 http://dx.doi.org/10.1038/sj.bjc.6605021

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