Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F

OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund’s adjuvant-induced and collagen-induced art...

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Autores principales: Paval, Jaijesh, Kaitheri, Srinivasan Keloth, Potu, Bhagath Kumar, Govindan, Sreejith, Kumar, Raju Suresh, Narayanan, Sareesh Naduvil, Moorkoth, Sudheer
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2009
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694464/
https://www.ncbi.nlm.nih.gov/pubmed/19488595
http://dx.doi.org/10.1590/S1807-59322009000400015
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author Paval, Jaijesh
Kaitheri, Srinivasan Keloth
Potu, Bhagath Kumar
Govindan, Sreejith
Kumar, Raju Suresh
Narayanan, Sareesh Naduvil
Moorkoth, Sudheer
author_facet Paval, Jaijesh
Kaitheri, Srinivasan Keloth
Potu, Bhagath Kumar
Govindan, Sreejith
Kumar, Raju Suresh
Narayanan, Sareesh Naduvil
Moorkoth, Sudheer
author_sort Paval, Jaijesh
collection PubMed
description OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund’s adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin. RESULTS: The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.
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spelling pubmed-26944642009-06-17 Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F Paval, Jaijesh Kaitheri, Srinivasan Keloth Potu, Bhagath Kumar Govindan, Sreejith Kumar, Raju Suresh Narayanan, Sareesh Naduvil Moorkoth, Sudheer Clinics (Sao Paulo) Basic Research OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund’s adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin. RESULTS: The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2009-04 /pmc/articles/PMC2694464/ /pubmed/19488595 http://dx.doi.org/10.1590/S1807-59322009000400015 Text en Copyright © 2009 Hospital das Clínicas da FMUSP
spellingShingle Basic Research
Paval, Jaijesh
Kaitheri, Srinivasan Keloth
Potu, Bhagath Kumar
Govindan, Sreejith
Kumar, Raju Suresh
Narayanan, Sareesh Naduvil
Moorkoth, Sudheer
Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F
title Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F
title_full Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F
title_fullStr Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F
title_full_unstemmed Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F
title_short Anti-Arthritic Potential of the Plant Justicia Gendarussa Burm F
title_sort anti-arthritic potential of the plant justicia gendarussa burm f
topic Basic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694464/
https://www.ncbi.nlm.nih.gov/pubmed/19488595
http://dx.doi.org/10.1590/S1807-59322009000400015
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