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Similar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas suggest a common pathway to tumorigenesis

BACKGROUND: Paragangliomas of the head and neck are highly vascular and usually clinically benign tumors arising in the paraganglia of the autonomic nervous system. A significant number of cases (10–50%) are proven to be familial. Multiple genes encoding subunits of the mitochondrial succinate-dehyd...

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Detalles Bibliográficos
Autores principales:	Hensen, Erik F, Goeman, Jelle J, Oosting, Jan, Van der Mey, Andel GL, Hogendoorn, Pancras CW, Cremers, Cor WRJ, Devilee, Peter, Cornelisse, Cees J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694828/ https://www.ncbi.nlm.nih.gov/pubmed/19432956 http://dx.doi.org/10.1186/1755-8794-2-25

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