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Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis

This study shows that the androgen receptor agonistic potency is clearly concealed by the effects of androgen receptor antagonists in a total sediment extract, demonstrating that toxicity screening of total extracts is not enough to evaluate the full in vitro endocrine disrupting potential of a comp...

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Detalles Bibliográficos
Autores principales: Weiss, Jana M., Hamers, Timo, Thomas, Kevin V., van der Linden, Sander, Leonards, Pim E. G., Lamoree, Marja H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694927/
https://www.ncbi.nlm.nih.gov/pubmed/19418041
http://dx.doi.org/10.1007/s00216-009-2807-8

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