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Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis
This study shows that the androgen receptor agonistic potency is clearly concealed by the effects of androgen receptor antagonists in a total sediment extract, demonstrating that toxicity screening of total extracts is not enough to evaluate the full in vitro endocrine disrupting potential of a comp...
Autores principales: | Weiss, Jana M., Hamers, Timo, Thomas, Kevin V., van der Linden, Sander, Leonards, Pim E. G., Lamoree, Marja H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694927/ https://www.ncbi.nlm.nih.gov/pubmed/19418041 http://dx.doi.org/10.1007/s00216-009-2807-8 |
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