Efficient siRNA Delivery into Primary Cells by Peptide Transduction-dsRNA Binding Domain (PTD-DRBD) Fusion Protein

Short interfering RNA (siRNA) induced RNA interference (RNAi) responses allow for discovery research and performing large scale screening1-5; however, due to their size and anionic charge, siRNAs have no bioavailability to enter cells4,5. Current approaches fail to deliver siRNAs into a high percent...

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Detalles Bibliográficos
Autores principales: Eguchi, Akiko, Meade, Bryan R., Chang, Yung-Chi, Fredrickson, Criag T., Willert, Karl, Puri, Nitin, Dowdy, Steven F.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694965/
https://www.ncbi.nlm.nih.gov/pubmed/19448630
http://dx.doi.org/10.1038/nbt.1541

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