Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline

Virtually all cases of cervical cancer are caused by persistent infections with a restricted set of human papillomaviruses (HPV). Some HPV types, like HPV16 and HPV18, are clear and powerful carcinogens. However, the categorization of the most weakly carcinogenic HPV types is extremely challenging....

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Detalles Bibliográficos
Autores principales: Schiffman, Mark, Clifford, Gary, Buonaguro, Franco M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694995/
https://www.ncbi.nlm.nih.gov/pubmed/19486508
http://dx.doi.org/10.1186/1750-9378-4-8
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author Schiffman, Mark
Clifford, Gary
Buonaguro, Franco M
author_facet Schiffman, Mark
Clifford, Gary
Buonaguro, Franco M
author_sort Schiffman, Mark
collection PubMed
description Virtually all cases of cervical cancer are caused by persistent infections with a restricted set of human papillomaviruses (HPV). Some HPV types, like HPV16 and HPV18, are clear and powerful carcinogens. However, the categorization of the most weakly carcinogenic HPV types is extremely challenging. The decisions are important for screening test and vaccine development. This article describes for open discussion an approach recently taken by a World Health Organization International Agency for Research on Cancer (IARC) Monographs Working Group to re-assess the carcinogenicity of different HPV types.
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spelling pubmed-26949952009-06-11 Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline Schiffman, Mark Clifford, Gary Buonaguro, Franco M Infect Agent Cancer Review Virtually all cases of cervical cancer are caused by persistent infections with a restricted set of human papillomaviruses (HPV). Some HPV types, like HPV16 and HPV18, are clear and powerful carcinogens. However, the categorization of the most weakly carcinogenic HPV types is extremely challenging. The decisions are important for screening test and vaccine development. This article describes for open discussion an approach recently taken by a World Health Organization International Agency for Research on Cancer (IARC) Monographs Working Group to re-assess the carcinogenicity of different HPV types. BioMed Central 2009-06-01 /pmc/articles/PMC2694995/ /pubmed/19486508 http://dx.doi.org/10.1186/1750-9378-4-8 Text en Copyright © 2009 Schiffman et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Schiffman, Mark
Clifford, Gary
Buonaguro, Franco M
Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
title Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
title_full Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
title_fullStr Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
title_full_unstemmed Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
title_short Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
title_sort classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694995/
https://www.ncbi.nlm.nih.gov/pubmed/19486508
http://dx.doi.org/10.1186/1750-9378-4-8
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