Progress and challenges in the vaccine-based treatment of head and neck cancers

Head and neck (HN) cancer represents one of the most challenging diseases because the mortality remains high despite advances in early diagnosis and treatment. Although vaccine-based approaches for the treatment of advanced squamous cell carcinoma of the head and neck have achieved limited clinical...

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Detalles Bibliográficos
Autor principal: Venuti, Aldo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695420/
https://www.ncbi.nlm.nih.gov/pubmed/19473517
http://dx.doi.org/10.1186/1756-9966-28-69
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author Venuti, Aldo
author_facet Venuti, Aldo
author_sort Venuti, Aldo
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description Head and neck (HN) cancer represents one of the most challenging diseases because the mortality remains high despite advances in early diagnosis and treatment. Although vaccine-based approaches for the treatment of advanced squamous cell carcinoma of the head and neck have achieved limited clinical success, advances in cancer immunology provide a strong foundation and powerful new tools to guide current attempts to develop effective cancer vaccines. This article reviews what has to be rather what has been done in the field for the development of future vaccines in HN tumours.
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spelling pubmed-26954202009-06-12 Progress and challenges in the vaccine-based treatment of head and neck cancers Venuti, Aldo J Exp Clin Cancer Res Review Head and neck (HN) cancer represents one of the most challenging diseases because the mortality remains high despite advances in early diagnosis and treatment. Although vaccine-based approaches for the treatment of advanced squamous cell carcinoma of the head and neck have achieved limited clinical success, advances in cancer immunology provide a strong foundation and powerful new tools to guide current attempts to develop effective cancer vaccines. This article reviews what has to be rather what has been done in the field for the development of future vaccines in HN tumours. BioMed Central 2009-05-27 /pmc/articles/PMC2695420/ /pubmed/19473517 http://dx.doi.org/10.1186/1756-9966-28-69 Text en Copyright © 2009 Venuti; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Venuti, Aldo
Progress and challenges in the vaccine-based treatment of head and neck cancers
title Progress and challenges in the vaccine-based treatment of head and neck cancers
title_full Progress and challenges in the vaccine-based treatment of head and neck cancers
title_fullStr Progress and challenges in the vaccine-based treatment of head and neck cancers
title_full_unstemmed Progress and challenges in the vaccine-based treatment of head and neck cancers
title_short Progress and challenges in the vaccine-based treatment of head and neck cancers
title_sort progress and challenges in the vaccine-based treatment of head and neck cancers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695420/
https://www.ncbi.nlm.nih.gov/pubmed/19473517
http://dx.doi.org/10.1186/1756-9966-28-69
work_keys_str_mv AT venutialdo progressandchallengesinthevaccinebasedtreatmentofheadandneckcancers

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