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Modeling of solvent-dependent conformational transitions in Burkholderia cepacia lipase
BACKGROUND: The characteristic of most lipases is the interfacial activation at a lipid interface or in non-polar solvents. Interfacial activation is linked to a large conformational change of a lid, from a closed to an open conformation which makes the active site accessible for substrates. While f...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695465/ https://www.ncbi.nlm.nih.gov/pubmed/19476626 http://dx.doi.org/10.1186/1472-6807-9-38 |