Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val(158)met Polymorphism

Increased pain sensitivity after opioid administration (opioid-induced hyperalgesia) and/or repeated painful stimuli is an individually varying and clinically important phenomenon. The functional polymorphism (val(158)met) of the Catechol-O-methyltransferase (COMT) gene regulates the metabolism of d...

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Detalles Bibliográficos
Autores principales: Jensen, Karin B., Lonsdorf, Tina B., Schalling, Martin, Kosek, Eva, Ingvar, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695541/
https://www.ncbi.nlm.nih.gov/pubmed/19547755
http://dx.doi.org/10.1371/journal.pone.0006016

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