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Impaired Interleukin-1β and c-Fos Expression in the Hippocampus Is Associated with a Spatial Memory Deficit in P2X(7) Receptor-Deficient Mice

Recent evidence suggests that interleukin-1β (IL-1β), which was originally identified as a proinflammatory cytokine, is also required in the brain for memory processes. We have previously shown that IL-1β synthesis in the hippocampus is dependent on P2X(7) receptor (P2X(7)R), which is an ionotropic...

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Detalles Bibliográficos
Autores principales: Labrousse, Virginie F., Costes, Laurence, Aubert, Agnès, Darnaudéry, Muriel, Ferreira, Guillaume, Amédée, Thierry, Layé, Sophie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695542/
https://www.ncbi.nlm.nih.gov/pubmed/19547756
http://dx.doi.org/10.1371/journal.pone.0006006

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