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Ligation of α-Dystroglycan on Podocytes Induces Intracellular Signaling: A New Mechanism for Podocyte Effacement?

BACKGROUND: α-Dystroglycan is a negatively charged glycoprotein that covers the apical and basolateral membrane of the podocyte. Its transmembrane binding to the cytoskeleton is regulated via tyrosine phosphorylation (pY892) of β-dystroglycan. At the basolateral side α-dystroglycan binds the glomeru...

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Detalles Bibliográficos
Autores principales:	Vogtländer, Nils P. J., Visch, Henk Jan, Bakker, Marinka A. H., Berden, Jo H. M., van der Vlag, Johan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695560/ https://www.ncbi.nlm.nih.gov/pubmed/19543532 http://dx.doi.org/10.1371/journal.pone.0005979

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