Memory deficits in APP23/Abca1(+/−) mice correlate with the level of Aβ oligomers

ABCA1, a member of the ATP-binding cassette family of transporters, lipidates ApoE (apolipoprotein A) and is essential for the generation of HDL (high-density lipoprotein)-like particles in the CNS (central nervous system). Lack of Abca1 increases amyloid deposition in several AD (Alzheimer's d...

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Detalles Bibliográficos
Autores principales: Lefterov, Iliya, Fitz, Nicholas F, Cronican, Andrea, Lefterov, Preslav, Staufenbiel, Matthias, Koldamova, Radosveta
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695585/
https://www.ncbi.nlm.nih.gov/pubmed/19570031
http://dx.doi.org/10.1042/AN20090015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695585/
https://www.ncbi.nlm.nih.gov/pubmed/19570031
http://dx.doi.org/10.1042/AN20090015

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