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Memory deficits in APP23/Abca1(+/−) mice correlate with the level of Aβ oligomers
ABCA1, a member of the ATP-binding cassette family of transporters, lipidates ApoE (apolipoprotein A) and is essential for the generation of HDL (high-density lipoprotein)-like particles in the CNS (central nervous system). Lack of Abca1 increases amyloid deposition in several AD (Alzheimer's d...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Neurochemistry
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695585/ https://www.ncbi.nlm.nih.gov/pubmed/19570031 http://dx.doi.org/10.1042/AN20090015 |