Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema

A common feature of lung disorders with poor treatment options, including emphysema, is a failure to initiate a repair process of the alveolar epithelium. Several putative stem cell niches in the lung thought to be involved in lung homeostasis have been described. Apparently, under pathophysiologica...

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Detalles Bibliográficos
Autores principales: Lenssen, Josephine, Stolk, Jan
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695612/
https://www.ncbi.nlm.nih.gov/pubmed/18044685
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author Lenssen, Josephine
Stolk, Jan
author_facet Lenssen, Josephine
Stolk, Jan
author_sort Lenssen, Josephine
collection PubMed
description A common feature of lung disorders with poor treatment options, including emphysema, is a failure to initiate a repair process of the alveolar epithelium. Several putative stem cell niches in the lung thought to be involved in lung homeostasis have been described. Apparently, under pathophysiological conditions these resident progenitor cells are unable to recover damaged alveolar epithelium, in particular in emphysema. The potential therapeutic effect of retinoic acid receptor agonists on various resident lung progenitor cells is reviewed.
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spelling pubmed-26956122009-06-16 Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema Lenssen, Josephine Stolk, Jan Int J Chron Obstruct Pulmon Dis Review A common feature of lung disorders with poor treatment options, including emphysema, is a failure to initiate a repair process of the alveolar epithelium. Several putative stem cell niches in the lung thought to be involved in lung homeostasis have been described. Apparently, under pathophysiological conditions these resident progenitor cells are unable to recover damaged alveolar epithelium, in particular in emphysema. The potential therapeutic effect of retinoic acid receptor agonists on various resident lung progenitor cells is reviewed. Dove Medical Press 2007-06 2007-06 /pmc/articles/PMC2695612/ /pubmed/18044685 Text en © 2007 Dove Medical Press Limited. All rights reserved
spellingShingle Review
Lenssen, Josephine
Stolk, Jan
Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
title Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
title_full Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
title_fullStr Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
title_full_unstemmed Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
title_short Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
title_sort pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695612/
https://www.ncbi.nlm.nih.gov/pubmed/18044685
work_keys_str_mv AT lenssenjosephine pulmonarystemcellsandtheinductionoftissueregenerationinthetreatmentofemphysema
AT stolkjan pulmonarystemcellsandtheinductionoftissueregenerationinthetreatmentofemphysema

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