T-regulatory cell modulation: the future of cancer immunotherapy?

T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulati...

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Detalles Bibliográficos
Autores principales: Nizar, S, Copier, J, Meyer, B, Bodman-Smith, M, Galustian, C, Kumar, D, Dalgleish, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695683/
https://www.ncbi.nlm.nih.gov/pubmed/19384299
http://dx.doi.org/10.1038/sj.bjc.6605040
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author Nizar, S
Copier, J
Meyer, B
Bodman-Smith, M
Galustian, C
Kumar, D
Dalgleish, A
author_facet Nizar, S
Copier, J
Meyer, B
Bodman-Smith, M
Galustian, C
Kumar, D
Dalgleish, A
author_sort Nizar, S
collection PubMed
description T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients.
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spelling pubmed-26956832010-06-02 T-regulatory cell modulation: the future of cancer immunotherapy? Nizar, S Copier, J Meyer, B Bodman-Smith, M Galustian, C Kumar, D Dalgleish, A Br J Cancer Minireview T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients. Nature Publishing Group 2009-06-02 2009-04-21 /pmc/articles/PMC2695683/ /pubmed/19384299 http://dx.doi.org/10.1038/sj.bjc.6605040 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Nizar, S
Copier, J
Meyer, B
Bodman-Smith, M
Galustian, C
Kumar, D
Dalgleish, A
T-regulatory cell modulation: the future of cancer immunotherapy?
title T-regulatory cell modulation: the future of cancer immunotherapy?
title_full T-regulatory cell modulation: the future of cancer immunotherapy?
title_fullStr T-regulatory cell modulation: the future of cancer immunotherapy?
title_full_unstemmed T-regulatory cell modulation: the future of cancer immunotherapy?
title_short T-regulatory cell modulation: the future of cancer immunotherapy?
title_sort t-regulatory cell modulation: the future of cancer immunotherapy?
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695683/
https://www.ncbi.nlm.nih.gov/pubmed/19384299
http://dx.doi.org/10.1038/sj.bjc.6605040
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