iNOS-Producing Inflammatory Dendritic Cells Constitute the Major Infected Cell Type during the Chronic Leishmania major Infection Phase of C57BL/6 Resistant Mice

Leishmania major parasites reside and multiply in late endosomal compartments of host phagocytic cells. Immune control of Leishmania growth absolutely requires expression of inducible Nitric Oxide Synthase (iNOS/NOS2) and subsequent production of NO. Here, we show that CD11b(+) CD11c(+) Ly-6C(+) MHC...

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Detalles Bibliográficos
Autores principales: De Trez, Carl, Magez, Stefan, Akira, Shizuo, Ryffel, Bernhard, Carlier, Yves, Muraille, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695779/
https://www.ncbi.nlm.nih.gov/pubmed/19557162
http://dx.doi.org/10.1371/journal.ppat.1000494

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