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Assessing the Impact of Transgenerational Epigenetic Variation on Complex Traits
Loss or gain of DNA methylation can affect gene expression and is sometimes transmitted across generations. Such epigenetic alterations are thus a possible source of heritable phenotypic variation in the absence of DNA sequence change. However, attempts to assess the prevalence of stable epigenetic...
Autores principales: | Johannes, Frank, Porcher, Emmanuelle, Teixeira, Felipe K., Saliba-Colombani, Vera, Simon, Matthieu, Agier, Nicolas, Bulski, Agnès, Albuisson, Juliette, Heredia, Fabiana, Audigier, Pascal, Bouchez, David, Dillmann, Christine, Guerche, Philippe, Hospital, Frédéric, Colot, Vincent |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696037/ https://www.ncbi.nlm.nih.gov/pubmed/19557164 http://dx.doi.org/10.1371/journal.pgen.1000530 |
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