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Analysis of Germline Variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in Familial and Sporadic Renal Cell Carcinoma

BACKGROUND: The investigation of rare familial forms of kidney cancer has provided important insights into the biology of sporadic renal cell carcinoma (RCC). In particular, the identification of the von Hippel Lindau (VHL) familial cancer syndrome gene (VHL) provided the basis for the discovery tha...

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Detalles Bibliográficos
Autores principales:	Ricketts, Christopher, Zeegers, Maurice P., Lubinski, Jan, Maher, Eamonn R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696041/ https://www.ncbi.nlm.nih.gov/pubmed/19551141 http://dx.doi.org/10.1371/journal.pone.0006037

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