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Activation of PPARγ by Rosiglitazone Does Not Negatively Impact Male Sex Steroid Hormones in Diabetic Rats

Peroxisome proliferator-activated receptor gamma (PPARγ) activation decreased serum testosterone (T) in women with hyperthecosis and/or polycystic ovary syndrome and reduced the conversion of androgens to estradiol (E2) in female rats. This implies modulation of female sex steroid hormones by PPARγ....

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Detalles Bibliográficos
Autores principales: Mansour, Mahmoud, Coleman, Elaine, Dennis, John, Akingbemi, Benson, Schwartz, Dean, Braden, Tim, Judd, Robert, Plaisance, Eric, Stewart, Laura Ken, Morrison, Edward
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696180/
https://www.ncbi.nlm.nih.gov/pubmed/19536350
http://dx.doi.org/10.1155/2009/101857

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