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Compensatory evolution for a gene deletion is not limited to its immediate functional network
BACKGROUND: Genetic disruption of an important phenotype should favor compensatory mutations that restore the phenotype. If the genetic basis of the phenotype is modular, with a network of interacting genes whose functions are specific to that phenotype, compensatory mutations are expected among the...
Autores principales: | Harcombe, WR, Springman, R, Bull, JJ |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696425/ https://www.ncbi.nlm.nih.gov/pubmed/19445716 http://dx.doi.org/10.1186/1471-2148-9-106 |
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