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Semaphorin 5B mediates synapse elimination in hippocampal neurons

BACKGROUND: Semaphorins are known to play an important role in axon guidance and growth by triggering dynamic rearrangements of the actin cytoskeleton in the neuronal growth cone. Intriguingly, some of these guidance molecules are persistently expressed after axonal pathfinding and target recognitio...

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Detalles Bibliográficos
Autores principales: O'Connor, Timothy P, Cockburn, Katie, Wang, Wenyan, Tapia, Lucia, Currie, Erin, Bamji, Shernaz X
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696441/
https://www.ncbi.nlm.nih.gov/pubmed/19463192
http://dx.doi.org/10.1186/1749-8104-4-18