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Inhibition of tyrosine kinase receptors by SU6668 promotes abnormal stromal development at the periphery of carcinomas

Dynamic contrast-enhanced (albumin-Gd-DTPA) magnetic resonance imaging, performed during 2 weeks of daily administration of an inhibitor of tyrosine kinase receptors (SU6668) in an HT-29 colon carcinoma model, revealed the onset of a hyper-enhancing rim, not observed in untreated tumours. To account...

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Detalles Bibliográficos
Autores principales:	Farace, P, Galiè, M, Merigo, F, Daducci, A, Calderan, L, Nicolato, E, Degrassi, A, Pesenti, E, Sbarbati, A, Marzola, P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696750/ https://www.ncbi.nlm.nih.gov/pubmed/19384298 http://dx.doi.org/10.1038/sj.bjc.6605041

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