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TGFBR1 variants TGFBR1(*)6A and Int7G24A are not associated with an increased familial colorectal cancer risk
Variants of the transforming growth factor-beta receptor type 1 (TGFBR1) gene, TGFBR1*6A and Int7G24A, have been suggested to act as low-penetrance tumour susceptibility alleles with TGFBR1*6A being causally responsible for some cases of familial colorectal cancer (CRC). We performed a case–control...
Autores principales: | Skoglund Lundin, J, Vandrovcova, J, Song, B, Zhou, X, Zelada-Hedman, M, Werelius, B, Houlston, R S, Lindblom, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696757/ https://www.ncbi.nlm.nih.gov/pubmed/19401691 http://dx.doi.org/10.1038/sj.bjc.6605054 |
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