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Activation of Wnt/β-catenin signalling pathway induces chemoresistance to interferon-α/5-fluorouracil combination therapy for hepatocellular carcinoma

Type I IFN receptor type 2 (IFNAR2) expression correlates significantly with clinical response to interferon (IFN)-α/5-fluorouracil (5-FU) combination therapy for hepatocellular carcinoma (HCC). However, some IFNAR2-positive patients show no response to the therapy. This result suggests the possibil...

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Detalles Bibliográficos
Autores principales:	Noda, T, Nagano, H, Takemasa, I, Yoshioka, S, Murakami, M, Wada, H, Kobayashi, S, Marubashi, S, Takeda, Y, Dono, K, Umeshita, K, Matsuura, N, Matsubara, K, Doki, Y, Mori, M, Monden, M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696759/ https://www.ncbi.nlm.nih.gov/pubmed/19401692 http://dx.doi.org/10.1038/sj.bjc.6605064

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