Cargando…

CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion

The aggressiveness of malignant melanoma is associated with differential expression of CXCL-8 and its receptors, CXCR1 and CXCR2. However, the precise functional role of these receptors in melanoma progression remains unclear. In this study, we investigate the precise functional role of CXCR1 and CX...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, S, Nannuru, K C, Sadanandam, A, Varney, M L, Singh, R K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696769/ https://www.ncbi.nlm.nih.gov/pubmed/19401689 http://dx.doi.org/10.1038/sj.bjc.6605055

Ejemplares similares

CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma
por: Werner, Thomas A, et al.
Publicado: (2017)

Role of chemokine receptor CXCR2 expression in mammary tumor growth, angiogenesis and metastasis
por: Nannuru, Kalyan C., et al.
Publicado: (2011)

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2
por: Bedognetti, D, et al.
Publicado: (2013)

Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis
por: Lee, Y S, et al.
Publicado: (2012)

CXCR2: A Novel Mediator of Mammary Tumor Bone Metastasis
por: Sharma, Bhawna, et al.
Publicado: (2019)

ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status
por: Feng, Hailiang, et al.
Publicado: (2018)

Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4
por: Schimanski, C C, et al.
Publicado: (2006)

CXCL9 induces chemotaxis, chemorepulsion and endothelial barrier disruption through CXCR3-mediated activation of melanoma cells
por: Amatschek, S, et al.
Publicado: (2011)

Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation
por: Sadanandam, A, et al.
Publicado: (2012)

Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
por: Yoshitake, N, et al.
Publicado: (2008)

Effect of the chemokine receptor CXCR7 on proliferation of carcinoma cells in vitro and in vivo
por: Meijer, J, et al.
Publicado: (2008)

In ovarian cancer the prognostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway
por: Pils, D, et al.
Publicado: (2007)

High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma
por: Maréchal, R, et al.
Publicado: (2009)

Alternative implication of CXCR4 in JAK2/STAT3 activation in small cell lung cancer
por: Pfeiffer, M, et al.
Publicado: (2009)

CXCR7 expression is associated with disease-free and disease-specific survival in cervical cancer patients
por: Schrevel, M, et al.
Publicado: (2012)

Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway
por: Wang, Z, et al.
Publicado: (2008)

HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in renal cell carcinoma
por: Micucci, Carla, et al.
Publicado: (2015)

Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer
por: Yang, Q, et al.
Publicado: (2014)

Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo
por: Winsel, S, et al.
Publicado: (2014)

Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis
por: Peng, F, et al.
Publicado: (2013)

Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis
por: Srivastava, S K, et al.
Publicado: (2015)

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
por: Braig, S, et al.
Publicado: (2011)

Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion
por: Berthier-Vergnes, O, et al.
Publicado: (2011)

Melanoma-expressed CD70 is involved in invasion and metastasis
por: Pich, Christine, et al.
Publicado: (2016)

MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells
por: Ponnusamy, M P, et al.
Publicado: (2008)

Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma
por: Ueno, K, et al.
Publicado: (2011)

Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1–PI3K–Rac1 pathway
por: Kamura, S, et al.
Publicado: (2010)

TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion
por: Boecke, A, et al.
Publicado: (2013)

CXCR2 signaling regulates KRAS((G12D))-induced autocrine growth of pancreatic cancer
por: Purohit, Abhilasha, et al.
Publicado: (2016)

Role of EIF5A2, a downstream target of Akt, in promoting melanoma cell invasion
por: Khosravi, S, et al.
Publicado: (2014)

Nuclear ING2 expression is reduced in human cutaneous melanomas
por: Lu, F, et al.
Publicado: (2006)

Collagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion
por: Sok, J C, et al.
Publicado: (2013)

Inhibition of transforming growth factor-β-activated kinase-1 blocks cancer cell adhesion, invasion, and metastasis
por: Ray, D M, et al.
Publicado: (2012)

Flexible, actin-based ridges colocalise with the β1 integrin on the surface of melanoma cells
por: Poole, K, et al.
Publicado: (2005)

MYB is a novel regulator of pancreatic tumour growth and metastasis
por: Srivastava, Sanjeev K, et al.
Publicado: (2015)

Potent anti-tumour activity of a novel conditionally replicating adenovirus for melanoma via inhibition of migration and invasion
por: Jiang, G, et al.
Publicado: (2014)

Protumoral roles of melanoma inhibitory activity 2 in oral squamous cell carcinoma
por: Kurihara, M, et al.
Publicado: (2013)

High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives
por: Janjetovic, Z, et al.
Publicado: (2011)

Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis
por: Walsh, N, et al.
Publicado: (2010)

Expression and functional role of CRIPTO-1 in cutaneous melanoma
por: De Luca, A, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_rb854tvurpq3j6v6mmtten6s5m