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A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila
BACKGROUND: The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines to be interrogated at genome-wide scale. However, multiple issues, such as off-target effects or low efficacie...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697172/ https://www.ncbi.nlm.nih.gov/pubmed/19435510 http://dx.doi.org/10.1186/1471-2164-10-220 |