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The efficiency of designs for fine-mapping of quantitative trait loci using combined linkage disequilibrium and linkage
In a simulation study, different designs were compared for efficiency of fine-mapping of QTL. The variance component method for fine-mapping of QTL was used to estimate QTL position and variance components. The design of many families with small size gave a higher mapping resolution than a design wi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697183/ https://www.ncbi.nlm.nih.gov/pubmed/15040896 http://dx.doi.org/10.1186/1297-9686-36-2-145 |